Skip Navigation

American Zoologist 1983 23(1):129-144; doi:10.1093/icb/23.1.129
© 1983 by The Society for Integrative and Comparative Biology
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Request Permissions
Google Scholar
Right arrow Articles by CHENG, T. C.
Right arrow Search for Related Content
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

The Role of Lysosomes in Molluscan Inflammation11

THOMAS C. CHENG
Marine Biomedical Research Program and Department of Anatomy (Cell Biology),Medical University of South Carolina Charleston, South Carolina 29412

Phagocytosis and related phenomena represent integral features of inflammation in all metazoans. Reviewed herein are the results of studies directed at understanding the role(s) of lysosomal enzymes synthesized and released from circulating hemocytes, especially granulocytes, of gastropods and bivalves as a result of challenge with exogenous, nonself materials. From what is known, most of the mechanisms underlying this inflammation-associated process parallel those of mammalian macrophages; however, immunoglobulins and most probably components of complement are not involved. The required energy for phagocytosis in molluscs appears to be derived from glycolysis alone. Furthermore, nitroblue tetrazolium reduction and the myeloperoxidase-H2O2-halide antimicrobial system, both characteristic of mammalian phagocytes, appear to be absent in molluscs. It is concluded that by studying phagocytosis by molluscan hemocytes, a great deal can be learned about the evolution of inflammatory response and its constitutent elements.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.